Addiction and SSRI Medications

Addiction and SSRI Medications
By Andy Alt / Mental Dimensions

June 26, 2008 – TIME magazine’s June 16, 2008 cover story by Mark Thompson was a detailed article about US troops being given antidepressant drugs to deal with battlefield stress. A quote from the article (p 41) states “The newer drugs have fewer side effects and, unlike earlier drugs, are generally not addictive or toxic, even when taken in large quantities.” This is false, and easily disproved. Ask current and former patients if they’ve ever had physical withdrawal symptoms after stopping use of an SSRI, or search the Internet for posts and articles written by patients about addiction to SSRI medication.

I personally have experienced withdrawal symptoms from both Paxil and Effexor. A close relative of mine has experienced withdrawal symptoms from Paxil. It’s a crime against humanity for pharmaceutical companies and physicians who manufacture and prescribe these drugs to intentionally and knowingly attempt to deceive — by omission or otherwise — their patients regarding the physically addictive properties of these drugs. It’s especially tragic since this crime is perpetrated on one of the most vulnerable demographic of the general population, and a demographic which is one of the least capable of defending themselves — due to the very nature of mental illness — against injustice or malpractice.

Full disclosure:
a) A recent patient information sheet for Effexor (copyright 2006), published by Wyeth Pharmaceuticals (manufacturer of Effexor) and given to me by my former psychiatrist does state, “When people suddenly stop using Effexor XR, they can get symptoms from stopping the medicine too fast. Some of these symptoms include:” and there are 24 symptoms listed. You can appreciate how it’s worded – the much more well-known phrase and word avoided are “physical addiction” and “withdrawal.” (The side effects are shown in a different section, and there are only 16 listed.)

b) I was aware of Effexor’s addictive quality before I started taking it, (due to research I did on the Internet) which made the decision an informed one, and a risk I was willing to accept; however, millions of people have been victims of neglect regarding this major component of their treatment.

I don’t advocate abandoning the use of SSRI’s, but only treating people with mental illness the same as treating people who are more likely to possess the ability to competently hire a lawyer and sue the pants off a doctor or corporation. I hope the truth about the addictive properties of SSRIs will be fully and honestly revealed to the public ASAP. If Wyeth – along with other pharmaceutical companies – doesn’t come out with it, I suppose TIME might have a story about it once our troops come home and cease use of the drugs.

(To read the preceding article in the Northfield News, visit http://northfieldnews.com/news.php?viewStory=23089)

Addendum, July 17, 2008 – I’ve recently been corrected, and informed that addiction is the wrong term in the case of SSRI medication; the medical community prefers physical dependence, but my American Heritage dictionary made no distinction between the two. I won’t quote from the dictionary here — an ample supply of definitions is available on the Internet.

Addendum, July 30, 2008 – Referring to a line from this article, “When people suddenly stop using Effexor XR, they can get symptoms from stopping the medicine too fast. Some of these symptoms include:”, I realized that statement is not only carefully worded to avoid the term addiction or physical dependence, but completely misleading. Although tapering off some of these medications gradually will ease withdrawal symptoms, in many cases it will not absolutely eliminate them. And the other side of the coin is that in some cases a person will never experience side effects or withdrawal. I suggest to anybody interested to research multiple sources of information if he or she would like to find a rough estimate of the actual ratio.

Addendum – Aug 21, 2008:

Cymbalta Withdrawal And Why Doctors Don’t Listen
Mental Health Notes has been reporting on her own experiences with Cymbalta withdrawal and published an interview with another patient who went through a hellish withdrawal from the drug. Even more, the patient’s doc ignored her problem and tried to get her further onto the medication merry-goround

Nine Million Brits Addicted To Anti-Depressants, Benzos, Etc.
The Daily Mail (UK) is reporting that as many as nine million Britons are addicted to anti-depressants, benzos, sleeping pills and pain killers. If it’s nine million there, then it’s likely to be at least three times higher in the US

See Also:

19 Responses to “Addiction and SSRI Medications”


  1. 1 zania July 18, 2008 at 12:48 pm

    I too was prescribed Effexor for depression and anxiety. It not only made me ill (nausia, stomach upsets, sleeplessness – none of which improved over time), but when my doctor transferred me to another antidepressant (a TCA, which I later came off of without any major effects), the side effects of withdrawing from Effexor were huge – increased anxiety, dizziness, more nausia… and a headache so bad that I had to be given a morphine shot to stop it.

    This play on words about addiction versus ‘physical dependency’ is the get out clause for the drug companies. I don’t care whether I am addicted or physically dependent, both can be disabling.

  2. 2 Andy Alt July 19, 2008 at 10:12 am

    Thank you for commenting, and sharing your own experience. In my article I didn’t elaborate on my withdrawal symptoms, but they were much more severe for me than Paxil. I had about 2-4 hours of broken sleep, anxiety, and of course that amount of sleep is disabling, as you put it. I was able to wean myself off it, over a 4-6 week period (the whole memory of that experience I don’t recall very well). I’ve since read that Benadryl can help with withdrawal from SSRI, but I’d recommend more research to anyone that tries it after me mentioning it. :)

    • 3 Rachael A July 29, 2009 at 11:02 am

      I agree. I’m getting off all my meds slowly.

  3. 4 zania July 20, 2008 at 7:30 am

    Yes, Benadryl could help with some of the effects – sleep disturbance for instance, but only if you have withdrawn completely from all antidepressant and (particularly) anti-anxiety medications, as it can exxagerate their effects and/or over-sedate you.
    (I just googled Benadryl to see)

    At least you might be able to sleep through some of the other side effects ;)

  4. 5 Andy Alt December 7, 2008 at 6:24 pm

    Source: MindFreedom – Petition Completed to Stop Drug Crisis in US Military

  5. 6 Ana December 9, 2008 at 10:33 am

    Hi Andy,
    I’ve spent 19 months tapering 225 mg Effexor. Felt all withdrawal symptoms. After three months off the drug living was impossible.
    I had to go back to Effexor 150 mg. I don’t think I’m the only one.
    I also consider it crime against humanity.
    Thank you for the post.

  6. 7 truthman30 December 17, 2008 at 6:26 am

    I myself was addicted to Paxil(called Seroxat in the UK), that drug almost destroyed my life.
    Check out my blog for the truth about this horrible SSRI medication.

  7. 8 Andy Alt December 23, 2008 at 2:54 pm

    December 22, 2008: A big pill for healthcare to swallow

    The drug companies have mastered the art of purchasing favorable results. In the same election cycle that brought record presidential fund-raising from grassroots donors, the pharmaceutical industry contributed over $22 million to members of Congress. It hedged contributions evenly between the Republican and Democratic parties for the first time in nearly 20 years. Pfizer, a longtime donor to the GOP, is now doling out 51 percent of its campaign contributions to Democratic candidates.

    December 23, 2008:

    The AWP litigation was filed in 2005 in Montgomery Circuit Court alleging massive overcharges to the Alabama Medicaid Agency over a period of 1991-2005 as a result of pharmaceutical companies misreporting and inflating prices for drugs.

    In the AWP litigation, the State contends that more than 70 drug manufacturers falsely inflated the price of drugs and reported these fictitious prices to a reporting service called First Databank.

    The manufacturers submitted prices called Wholesale Acquisition Cost (WAC) and AWP to these reporting services, knowing those prices bore no relation at all to real marketplace prices, but would be used by state Medicaid programs in reimbursement.

    Alabama Medicaid, like most other states, reimburses pharmacies and doctors based on the prices submitted by the manufacturers and published by First Databank…Read more at Attorney General announces $28-million in new settlements with drug companies

    And a step forward: Glaxo Plans to End Political Donations

    Extra commentary: Glaxo Plans to End Political Donations

    • 9 Jane August 2, 2009 at 1:45 pm

      Thanks for the visit the other day Andy. Good to see you are still blogging. Speaking on a related note about addictions I enjoyed your article about smoking and depression.

      Anyhoo. These pharma guys are scum. It pains me to read this stuff though. The good guys are not going to win this for a long time. There is too much money to be milked off people. This will continue and persist for the foreseeable future. The cycle will start anew with each new patent.

      I was on the front lines when the first wonder SSRI, Prozac, was suddenly on the lips of every P doc and shrink. I once watched a boy my own age being put on Prozac at a group home for labeled teens in 1992. This kid went into seizures at the breakfast table right next to mine one morning. It was so horrible to watch and to know the Prozac did it to him. That this was the supposed chemical rebalancing.

      Witnessing that I knew I would never try SSRIs no matter how bad I felt. That saved me from having my own SSRI war stories on my blog. >.<

      Prior to that experience I had been force hospitalized against my will for behavior that was unfortunately but inaccurately assumed to be suicidal. On my first appointment with the Pdoc in charge of case he asked me if I had been on meds before. I said that I had and that it was horrible. Then he tried pushing Prozac on me which I refused.

      About four years later I found myself in front of another Pdoc after another forced hospitalization for a genuine and serious suicide attempt. Eerily this guy also tried pushing Prozac on me which I refused yet again.

      I remember thinking that was something really wrong going on here. Was there a policy I wasn't aware of that forced Pdocs to push drugs on you? I could see if I asked for a pill but I never asked for one! These Prozac pitches were always unasked for and unsolicited.

      From reading these horrible antidepressant addiction stories ten, almost twenty years afterward my skin crawls to think about these doctors pressing and pushing me to try an SSRI.

  8. 10 Bloggerwithocd September 18, 2009 at 7:09 pm

    Does the presence of withdrawal symptoms necessarily suggest addiction?

    Bloggerwithocd writes about what it’s like to live with Obsessive Compulsive Disorder at http://www.itsmewithocd.blogspot.com.

  9. 11 Andy Alt September 18, 2009 at 10:32 pm

    Pasted from above:

    Addendum, July 17, 2008 – I’ve recently been corrected, and informed that addiction is the wrong term in the case of SSRI medication; the medical community prefers physical dependence, but my American Heritage dictionary made no distinction between the two. I won’t quote from the dictionary here — an ample supply of definitions is available on the Internet.

    The presence of withdrawal symptoms can indicate either addiction or physical dependence.


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